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Antifungal activity of Co(II) and Cu(II) complexes containing 1,3-bis(benzotriazol-1-yl)-propan-2-ol on the growth and virulence traits of fluconazole-resistant Candida species: synthesis, DFT calculations, and biological activity

Relevant virulence traits in Candida spp. are associated with dimorphic change and biofilm formation, which became an important target to reduce antifungal resistance. In this work, Co(II) complexes containing a benzotriazole derivative ligand showed a promising capacity of reducing these virulence...

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Detalles Bibliográficos
Autores principales: Murcia-Galán, Ricardo A., Durán, Sandra M., Leal-Pinto, Sandra M., Roa-Cordero, Martha V., Vargas, Jose D., Herrera, Laura V., Muñoz-Castro, Alvaro, MacLeod-Carey, Desmond, Naranjo, Tonny W., Rodríguez-Kessler, Peter L., Hurtado, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563319/
https://www.ncbi.nlm.nih.gov/pubmed/37817173
http://dx.doi.org/10.1186/s13065-023-01037-7