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Regulatory T cells contribute to the immunosuppressive phenotype of neutrophils in a mouse model of chronic lymphocytic leukemia

BACKGROUND: Impaired neutrophil activity is an important issue in chronic lymphocytic leukemia (CLL), as it contributes to a dysfunctional immune response leading to life-threatening infections in patients. Some features typical of CLL neutrophils, e.g., the B-cell-supportive secretion profile, have...

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Detalles Bibliográficos
Autores principales: Goral, Agnieszka, Sledz, Marta, Manda-Handzlik, Aneta, Cieloch, Adrianna, Wojciechowska, Alicja, Lachota, Mieszko, Mroczek, Agnieszka, Demkow, Urszula, Zagozdzon, Radoslaw, Matusik, Katarzyna, Wachowska, Malgorzata, Muchowicz, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563345/
https://www.ncbi.nlm.nih.gov/pubmed/37817276
http://dx.doi.org/10.1186/s40164-023-00452-9