Dispensable Role of Aire in CD11c(+) Conventional Dendritic Cells for Antigen Presentation and Shaping the Transcriptome
Aire, the defect of which is responsible for the development of autoimmunity, is predominantly expressed in medullary thymic epithelial cells, and it controls a wide variety of genes, including those of tissue-restricted Ags, for establishing thymic tolerance. Aire is also expressed from APCs in the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563386/ https://www.ncbi.nlm.nih.gov/pubmed/36695731 http://dx.doi.org/10.4049/immunohorizons.2200103 |