Dispensable Role of Aire in CD11c(+) Conventional Dendritic Cells for Antigen Presentation and Shaping the Transcriptome

Aire, the defect of which is responsible for the development of autoimmunity, is predominantly expressed in medullary thymic epithelial cells, and it controls a wide variety of genes, including those of tissue-restricted Ags, for establishing thymic tolerance. Aire is also expressed from APCs in the...

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Detalles Bibliográficos
Autores principales: Miyazawa, Ryuichiro, Nagao, Jun-ichi, Arita-Morioka, Ken-ichi, Matsumoto, Minoru, Morimoto, Junko, Yoshida, Masaki, Oya, Takeshi, Tsuneyama, Koichi, Yoshida, Hideyuki, Tanaka, Yoshihiko, Matsumoto, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563386/
https://www.ncbi.nlm.nih.gov/pubmed/36695731
http://dx.doi.org/10.4049/immunohorizons.2200103