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Peptides disrupting TM4SF3 interaction with AR or AR-V7 block prostate cancer cell proliferation
Androgen receptor (AR) plays a vital role in the development and progression of prostate cancer from the primary stage to the usually lethal stage known as castration-resistant prostate cancer (CRPC). Constitutively active AR splice variants (AR-Vs) lacking the ligand-binding domain are partially re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563598/ https://www.ncbi.nlm.nih.gov/pubmed/37822366 http://dx.doi.org/10.1530/EO-23-0010 |