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Peptides disrupting TM4SF3 interaction with AR or AR-V7 block prostate cancer cell proliferation

Androgen receptor (AR) plays a vital role in the development and progression of prostate cancer from the primary stage to the usually lethal stage known as castration-resistant prostate cancer (CRPC). Constitutively active AR splice variants (AR-Vs) lacking the ligand-binding domain are partially re...

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Detalles Bibliográficos
Autores principales: Khatiwada, Prabesh, Rimal, Ujjwal, Malla, Mamata, Han, Zhengyang, Shemshedini, Lirim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563598/
https://www.ncbi.nlm.nih.gov/pubmed/37822366
http://dx.doi.org/10.1530/EO-23-0010