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Mitochondrial Ca(2+) uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses

Long-term changes in synaptic strength form the basis of learning and memory. These changes rely upon energy-demanding mechanisms, which are regulated by local Ca(2+) signalling. Mitochondria are optimised for providing energy and buffering Ca(2+). However, our understanding of the role of mitochond...

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Detalles Bibliográficos
Autores principales: Devine, Michael J., Szulc, Blanka R., Howden, Jack H., López-Doménech, Guillermo, Ruiz, Arnaud, Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563808/
https://www.ncbi.nlm.nih.gov/pubmed/36274588
http://dx.doi.org/10.1242/jcs.259823