Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (...

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Autores principales: Liu, Li-Hong, Zhang, Han-Wen, Zhang, Hong-Bo, Liu, Xiao-Lei, Deng, Hua-Zhen, Lin, Fan, Huang, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563853/
https://www.ncbi.nlm.nih.gov/pubmed/37823021
http://dx.doi.org/10.4329/wjr.v15.i9.274
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author Liu, Li-Hong
Zhang, Han-Wen
Zhang, Hong-Bo
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
Huang, Biao
author_facet Liu, Li-Hong
Zhang, Han-Wen
Zhang, Hong-Bo
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
Huang, Biao
author_sort Liu, Li-Hong
collection PubMed
description BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy. CONCLUSION: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.
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spelling pubmed-105638532023-10-11 Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report Liu, Li-Hong Zhang, Han-Wen Zhang, Hong-Bo Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan Huang, Biao World J Radiol Case Report BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy. CONCLUSION: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management. Baishideng Publishing Group Inc 2023-09-28 2023-09-28 /pmc/articles/PMC10563853/ /pubmed/37823021 http://dx.doi.org/10.4329/wjr.v15.i9.274 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Liu, Li-Hong
Zhang, Han-Wen
Zhang, Hong-Bo
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
Huang, Biao
Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title_full Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title_fullStr Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title_full_unstemmed Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title_short Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
title_sort distinctive magnetic resonance imaging features in primary central nervous system lymphoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563853/
https://www.ncbi.nlm.nih.gov/pubmed/37823021
http://dx.doi.org/10.4329/wjr.v15.i9.274
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