Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563853/ https://www.ncbi.nlm.nih.gov/pubmed/37823021 http://dx.doi.org/10.4329/wjr.v15.i9.274 |
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author | Liu, Li-Hong Zhang, Han-Wen Zhang, Hong-Bo Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan Huang, Biao |
author_facet | Liu, Li-Hong Zhang, Han-Wen Zhang, Hong-Bo Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan Huang, Biao |
author_sort | Liu, Li-Hong |
collection | PubMed |
description | BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy. CONCLUSION: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management. |
format | Online Article Text |
id | pubmed-10563853 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-105638532023-10-11 Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report Liu, Li-Hong Zhang, Han-Wen Zhang, Hong-Bo Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan Huang, Biao World J Radiol Case Report BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy. CONCLUSION: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management. Baishideng Publishing Group Inc 2023-09-28 2023-09-28 /pmc/articles/PMC10563853/ /pubmed/37823021 http://dx.doi.org/10.4329/wjr.v15.i9.274 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Liu, Li-Hong Zhang, Han-Wen Zhang, Hong-Bo Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan Huang, Biao Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title | Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title_full | Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title_fullStr | Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title_full_unstemmed | Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title_short | Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report |
title_sort | distinctive magnetic resonance imaging features in primary central nervous system lymphoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563853/ https://www.ncbi.nlm.nih.gov/pubmed/37823021 http://dx.doi.org/10.4329/wjr.v15.i9.274 |
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