IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function

Canonical interleukin-2 (IL-2) signaling via the high-affinity CD25-containing IL-2 receptor-Janus kinase (JAK) 1,3-signal transducer and activator of transcription 5 (STAT5) pathway is essential for development and maintenance of CD4(+)CD25(Hi)Foxp3(+) regulatory T cells (Tregs) that support immune...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Lee, Ho-Sup, Kim, Sarah Hyun-Ji, de Lima, Mikhael Fernandes, Gingras, Alexandre R., Du, Qinyi, McLaughlin, Wilma, Ablack, Jailail, Lopez-Ramirez, Miguel A., Lagarrigue, Frederic, Fan, Zhichao, Chang, John T., VanDyke, Derek, Spangler, Jamie B., Ginsberg, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564087/
https://www.ncbi.nlm.nih.gov/pubmed/37598341
http://dx.doi.org/10.1016/j.celrep.2023.112996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564087/
https://www.ncbi.nlm.nih.gov/pubmed/37598341
http://dx.doi.org/10.1016/j.celrep.2023.112996

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