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Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates

The past few decades have been plagued by an increasing number of infections caused by antibiotic resistant bacteria. To mitigate the rise in untreatable infections, we need new antibiotics with novel targets and drug combinations that reduce resistance development. The novel β-clamp targeting antim...

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Detalles Bibliográficos
Autores principales: Singleton, Amanda Holstad, Bergum, Olaug Elisabeth Torheim, Søgaard, Caroline Krogh, Røst, Lisa Marie, Olsen, Cecilie Elisabeth, Blindheim, Fredrik Heen, Ræder, Synnøve Brandt, Bjørnstad, Frithjof A., Sundby, Eirik, Hoff, Bård Helge, Bruheim, Per, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564113/
https://www.ncbi.nlm.nih.gov/pubmed/37822747
http://dx.doi.org/10.3389/fmicb.2023.1260120