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Identification and analysis of individuals who deviate from their genetically-predicted phenotype

Findings from genome-wide association studies have facilitated the generation of genetic predictors for many common human phenotypes. Stratifying individuals misaligned to a genetic predictor based on common variants may be important for follow-up studies that aim to identify alternative causal fact...

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Detalles Bibliográficos
Autores principales: Hawkes, Gareth, Yengo, Loic, Vedantam, Sailaja, Marouli, Eirini, Beaumont, Robin N., Tyrrell, Jessica, Weedon, Michael N., Hirschhorn, Joel, Frayling, Timothy M., Wood, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564121/
https://www.ncbi.nlm.nih.gov/pubmed/37733769
http://dx.doi.org/10.1371/journal.pgen.1010934