Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury

Sirtuin 3 (SIRT3), the main deacetylase of mitochondria, modulates the acetylation levels of substrates governing metabolism and oxidative stress. In the kidney, we showed that SIRT3 affects the proper functioning of high energy-demanding cells, such as tubular cells and podocytes. Less is known abo...

Descripción completa

Detalles Bibliográficos
Autores principales: Pezzotta, Anna, Perico, Luca, Corna, Daniela, Morigi, Marina, Remuzzi, Giuseppe, Benigni, Ariela, Imberti, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564163/
https://www.ncbi.nlm.nih.gov/pubmed/37816025
http://dx.doi.org/10.1371/journal.pone.0291909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564163/
https://www.ncbi.nlm.nih.gov/pubmed/37816025
http://dx.doi.org/10.1371/journal.pone.0291909

Ejemplares similares