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Metabolic and mitochondrial dysregulation in CD4(+) T cells from HIV-positive women on combination anti-retroviral therapy

BACKGROUND: For optimal functionality, immune cells require a robust and adaptable metabolic program that is fueled by dynamic mitochondrial activity. In this study, we investigate the metabolic alterations occurring in immune cells during HIV infection and antiretroviral therapy by analyzing the up...

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Detalles Bibliográficos
Autores principales: Akiso, Matrona, Ameka, Magdalene, Naidoo, Kewreshini, Langat, Robert, Kombo, Janet, Sikuku, Delories, Ndung’u, Thumbi, Altfeld, Marcus, Anzala, Omu, Mureithi, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564234/
https://www.ncbi.nlm.nih.gov/pubmed/37816026
http://dx.doi.org/10.1371/journal.pone.0286436