Cargando…
Metabolic and mitochondrial dysregulation in CD4(+) T cells from HIV-positive women on combination anti-retroviral therapy
BACKGROUND: For optimal functionality, immune cells require a robust and adaptable metabolic program that is fueled by dynamic mitochondrial activity. In this study, we investigate the metabolic alterations occurring in immune cells during HIV infection and antiretroviral therapy by analyzing the up...
Autores principales: | Akiso, Matrona, Ameka, Magdalene, Naidoo, Kewreshini, Langat, Robert, Kombo, Janet, Sikuku, Delories, Ndung’u, Thumbi, Altfeld, Marcus, Anzala, Omu, Mureithi, Marianne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564234/ https://www.ncbi.nlm.nih.gov/pubmed/37816026 http://dx.doi.org/10.1371/journal.pone.0286436 |
Ejemplares similares
-
Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients
por: Mlimi, Hlelolwenkosi, et al.
Publicado: (2022) -
Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection
por: Naidoo, Kewreshini K., et al.
Publicado: (2021) -
Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans
por: Naidoo, Kewreshini K., et al.
Publicado: (2019) -
Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles
por: Moyano, Ana, et al.
Publicado: (2023) -
The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans
por: Naidoo, Kewreshini K., et al.
Publicado: (2020)