A data integration approach unveils a transcriptional signature of type 2 diabetes progression in rat and human islets

Pancreatic islet failure is a key characteristic of type 2 diabetes besides insulin resistance. To get molecular insights into the pathology of islets in type 2 diabetes, we developed a computational approach to integrating expression profiles of Goto-Kakizaki and Wistar rat islets from a designed e...

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Detalles Bibliográficos
Autores principales: Cao, Shenghao, Wang, Linting, Feng, Yance, Peng, Xiao-ding, Li, Lei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564241/
https://www.ncbi.nlm.nih.gov/pubmed/37816033
http://dx.doi.org/10.1371/journal.pone.0292579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564241/
https://www.ncbi.nlm.nih.gov/pubmed/37816033
http://dx.doi.org/10.1371/journal.pone.0292579

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