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A data integration approach unveils a transcriptional signature of type 2 diabetes progression in rat and human islets
Pancreatic islet failure is a key characteristic of type 2 diabetes besides insulin resistance. To get molecular insights into the pathology of islets in type 2 diabetes, we developed a computational approach to integrating expression profiles of Goto-Kakizaki and Wistar rat islets from a designed e...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564241/ https://www.ncbi.nlm.nih.gov/pubmed/37816033 http://dx.doi.org/10.1371/journal.pone.0292579 |