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M2 macrophage-derived exosomal miR-486-5p influences the differentiation potential of bone marrow mesenchymal stem cells and osteoporosis

Background: An imbalance between osteogenesis and adipogenesis in bone marrow mesenchymal stem cells (BMMSCs) can cause osteoporosis. Macrophage-derived exosomes (MD-Exos) and microRNAs (miRNAs) enriched in exosomes participate in the differentiation of BMMSCs. Methods: Bioinformatics methods were u...

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Detalles Bibliográficos
Autores principales: Liu, Jincheng, Sun, Zhenqian, You, Yunhao, Zhang, Lu, Hou, Dehui, Gu, Guanghui, Chen, Yunzhen, Jiao, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564417/
https://www.ncbi.nlm.nih.gov/pubmed/37751585
http://dx.doi.org/10.18632/aging.205031