Cargando…

M2 macrophage-derived exosomal miR-486-5p influences the differentiation potential of bone marrow mesenchymal stem cells and osteoporosis

Background: An imbalance between osteogenesis and adipogenesis in bone marrow mesenchymal stem cells (BMMSCs) can cause osteoporosis. Macrophage-derived exosomes (MD-Exos) and microRNAs (miRNAs) enriched in exosomes participate in the differentiation of BMMSCs. Methods: Bioinformatics methods were u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jincheng, Sun, Zhenqian, You, Yunhao, Zhang, Lu, Hou, Dehui, Gu, Guanghui, Chen, Yunzhen, Jiao, Guangjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564417/ https://www.ncbi.nlm.nih.gov/pubmed/37751585 http://dx.doi.org/10.18632/aging.205031

Ejemplares similares

WTAP-mediated m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis
por: You, Yunhao, et al.
Publicado: (2023)

Exosomal MiR-199a-5p Inhibits Tumorigenesis and Angiogenesis by Targeting VEGFA in Osteosarcoma
por: Zhang, Lu, et al.
Publicado: (2022)

WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis
por: Liu, Jincheng, et al.
Publicado: (2023)

Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation
por: Zhang, Lu, et al.
Publicado: (2023)

Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion
por: Zhang, Lu, et al.
Publicado: (2020)

Exosomes from Bone Marrow Mesenchymal Stem Cells Inhibit Neuronal Apoptosis and Promote Motor Function Recovery via the Wnt/β-catenin Signaling Pathway
por: Li, Ci, et al.
Publicado: (2019)

Bionic Tiger‐Bone Powder Improves Bone Microstructure and Bone Biomechanical Strength of Ovariectomized Rats
por: Ren, Shanwu, et al.
Publicado: (2021)

The PAX3-FOXO1 oncogene alters exosome miRNA content and leads to paracrine effects mediated by exosomal miR-486
por: Ghamloush, Farah, et al.
Publicado: (2019)

Down-regulation of miR-486-5p expression inhibits the proliferation and invasion of human extravillous trophoblasts, and decreased peripheral plasma miR-486-5p level is associated with human early pregnancy loss: Role of miR-486-5p in human early pregnancy loss
por: Gu, Yan, et al.
Publicado: (2023)

Exosomal Transfer of Macrophage-Derived miR-223 Confers Doxorubicin Resistance in Gastric Cancer
por: Gao, Huijie, et al.
Publicado: (2020)

Tanshinone IIA protects against chronic obstructive pulmonary disease via exosome-shuttled miR-486-5p
por: Tian, Dongdong, et al.
Publicado: (2022)

Silencing of miR-486 alleviates LPS-stimulated inflammatory response of macrophages through targeting SIRT1
por: Huang, Jie, et al.
Publicado: (2019)

Characterization of the functional effects of ferredoxin 1 as a cuproptosis biomarker in cancer
por: Li, Xiang, et al.
Publicado: (2022)

miR-486 is modulated by stretch and increases ventricular growth
por: Lange, Stephan, et al.
Publicado: (2019)

Exosomal miR-483-5p in Bone Marrow Mesenchymal Stem Cells Promotes Malignant Progression of Multiple Myeloma by Targeting TIMP2
por: Gu, Jianmei, et al.
Publicado: (2022)

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization
por: Zhang, Jiyong, et al.
Publicado: (2020)

Lipopolysaccharide-activated macrophages regulate the osteogenic differentiation of bone marrow mesenchymal stem cells through exosomes
por: Song, Xiao, et al.
Publicado: (2022)

Mesenchymal stem/stromal cells-derived exosomes for osteoporosis treatment
por: Huo, Kai-Lun, et al.
Publicado: (2023)

Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress
por: Lin, Xian-Ming, et al.
Publicado: (2021)

LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal
por: Zhu, Guanghui, et al.
Publicado: (2022)

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition
por: Zhang, Xiaoguang, et al.
Publicado: (2016)

Microarray analysis of circRNAs sequencing profile in exosomes derived from bone marrow mesenchymal stem cells in postmenopausal osteoporosis patients
por: Fu, Miao, et al.
Publicado: (2021)

The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma
por: Tomioka, Yuya, et al.
Publicado: (2023)

Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2
por: Hu, Huihui, et al.
Publicado: (2020)

BMSC-Derived Exosomes Inhibit Dexamethasone-Induced Muscle Atrophy via the miR-486-5p/FoxO1 Axis
por: Li, Ziyi, et al.
Publicado: (2021)

Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
por: Jin, Yi, et al.
Publicado: (2021)

Mechanisms of Zuogui Pill in Treating Osteoporosis: Perspective from Bone Marrow Mesenchymal Stem Cells
por: Yang, Aofei, et al.
Publicado: (2018)

Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction
por: Zhang, Rui, et al.
Publicado: (2015)

Exosomal transfer of bone marrow mesenchymal stem cell-derived miR-340 attenuates endometrial fibrosis
por: Xiao, Bang, et al.
Publicado: (2019)

Retraction: Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2
Publicado: (2021)

Exosome‑delivered miR‑486‑3p inhibits the progression of osteosarcoma via sponging CircKEAP1/MARCH1 axis components
por: Yang, Huidong, et al.
Publicado: (2023)

miR-486 suppresses the development of osteosarcoma by regulating PKC-δ pathway
por: He, Ming, et al.
Publicado: (2017)

miR-486-5p expression is regulated by DNA methylation in osteosarcoma
por: Namløs, Heidi M., et al.
Publicado: (2022)

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome
por: Samani, Adrienne, et al.
Publicado: (2022)

miR-486 suppresses the development of osteosarcoma by regulating PKC-δ pathway
por: He, Ming, et al.
Publicado: (2023)

Melatonin promotes bone marrow mesenchymal stem cell osteogenic differentiation and prevents osteoporosis development through modulating circ_0003865 that sponges miR-3653-3p
por: Wang, Xudong, et al.
Publicado: (2021)

Exosomes: A new option for osteoporosis treatment
por: Huang, Guijiang, et al.
Publicado: (2022)

Exosomes secreted from miRNA-29b-modified mesenchymal stem cells repaired spinal cord injury in rats
por: Yu, Tao, et al.
Publicado: (2019)

Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo
por: Wang, Jinkui, et al.
Publicado: (2022)

Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial–mesenchymal transition during radiation-induced pulmonary fibrosis
por: Yan, Ziyan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_elmlu7htvetqn2ojmahnagn02g