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Myeloid-specific knockout of SHP2 regulates PI3K/PLCγ signaling pathway to protect against early myocardial infarction injury

Objectives: To study the effects of myeloid-specific knockout of SHP2 on early myocardial infarction and explore its molecular mechanism. Methods: The model of myocardial infarction was established by using SHP2 in myeloid-specific knockout mice, and the effect of SHP2MAC-KO on myocardial function w...

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Detalles Bibliográficos
Autores principales: Sha, Menglin, Li, Hongxing, Guo, Bingyan, Geng, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564428/
https://www.ncbi.nlm.nih.gov/pubmed/37768203
http://dx.doi.org/10.18632/aging.205096