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Identification of the mitochondrial protein POLRMT as a potential therapeutic target of prostate cancer

RNA polymerase mitochondria (POLRMT) is essential for mitochondrial transcription machinery and other mitochondrial functions. Its expression and potential functions in prostate cancer were explored here. The Cancer Genome Atlas prostate cancer cohort (TCGA PRAD) shows that POLRMT mRNA expression is...

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Detalles Bibliográficos
Autores principales: Li, Xiaojun, Yao, Linya, Wang, Tao, Gu, Xiaolei, Wu, Yufan, Jiang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564732/
https://www.ncbi.nlm.nih.gov/pubmed/37816734
http://dx.doi.org/10.1038/s41419-023-06203-2