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Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
We previously found that global deletion of the mitochondrial enzyme arginase 2 (A2) limits optic nerve crush (ONC)-induced neuronal death. Herein, we examined the cell-specific role of A2 in this pathology by studies using wild type (WT), neuronal-specific calbindin 2 A2 KO (Calb2(cre/+) A2 (f/f)),...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564748/ https://www.ncbi.nlm.nih.gov/pubmed/37816735 http://dx.doi.org/10.1038/s41419-023-06180-6 |