Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush

We previously found that global deletion of the mitochondrial enzyme arginase 2 (A2) limits optic nerve crush (ONC)-induced neuronal death. Herein, we examined the cell-specific role of A2 in this pathology by studies using wild type (WT), neuronal-specific calbindin 2 A2 KO (Calb2(cre/+) A2 (f/f)),...

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Detalles Bibliográficos
Autores principales: Zaidi, Syed A. H., Xu, Zhimin, Lemtalsi, Tahira, Sandow, Porsche, Athota, Sruthi, Liu, Fang, Haigh, Stephen, Huo, Yuqing, Narayanan, S. Priya, Fulton, David J. R., Rojas, Modesto A., Fouda, Abdelrahman Y., Caldwell, Robert W., Caldwell, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564748/
https://www.ncbi.nlm.nih.gov/pubmed/37816735
http://dx.doi.org/10.1038/s41419-023-06180-6

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