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Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice

Although macrophages contribute to cancer cell dissemination, immune evasion, and metastatic outgrowth, they have also been reported to coordinate tumor-specific immune responses. We therefore hypothesized that macrophage polarization could be modulated therapeutically to prevent metastasis. Here, w...

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Detalles Bibliográficos
Autores principales: Thomas, Stacy K., Wattenberg, Max M., Choi-Bose, Shaanti, Uhlik, Mark, Harrison, Ben, Coho, Heather, Cassella, Christopher R., Stone, Meredith L., Patel, Dhruv, Markowitz, Kelly, Delman, Devora, Chisamore, Michael, Drees, Jeremy, Bose, Nandita, Beatty, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564762/
https://www.ncbi.nlm.nih.gov/pubmed/37816712
http://dx.doi.org/10.1038/s41467-023-41771-z