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Solubility measurement of verapamil for the preparation of developed nanomedicines using supercritical fluid

A static method is employed to determine the solubilities of verapamil in supercritical carbon dioxide (SC-CO(2)) at temperatures between 308 and 338 K and pressures between 12 and 30 MPa. The solubility of verapamil in SC-CO(2) expressed as mole fraction are in the range of 3.6 × 10(–6) to 7.14 × 1...

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Detalles Bibliográficos
Autores principales: Esfandiari, Nadia, Saadati Ardestani, Nedasadat, Alwi, Ratna Surya, Rojas, Adrián, Garlapati, Chandrasekhar, Sajadian, Seyed Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564778/
https://www.ncbi.nlm.nih.gov/pubmed/37816767
http://dx.doi.org/10.1038/s41598-023-44280-7