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Safety and tolerability of oral vorolanib for neovascular (wet) age-related macular degeneration: a phase I, open-label study

OBJECTIVE: To evaluate the efficacy and safety of oral vorolanib for the treatment of neovascular (wet) age-related macular degeneration (nAMD). METHODS: In the dose escalation, participants received ascending doses of oral vorolanib (25–100 mg daily). In the dose expansion, participants received re...

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Detalles Bibliográficos
Autores principales: Gao, Yunxia, Lu, Fang, Li, Xiaoxin, Dai, Hong, Liu, Kun, Liu, Xiaoling, Sun, Zuhua, Xiang, Jin, Ding, Lieming, Liang, Chris, Wang, Yang, Shen, Zhilin, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564794/
https://www.ncbi.nlm.nih.gov/pubmed/37041349
http://dx.doi.org/10.1038/s41433-023-02496-x