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Disabled-2: a protein up-regulated by high molecular weight hyaluronan has both tumor promoting and tumor suppressor roles in ovarian cancer

Although the pro-tumorigenic functions of hyaluronan (HA) are well documented there is limited information on the effects and targets of different molecular weight HA. Here, we investigated the effects of 27 kDa, 183 kDa and 1000 kDa HA on ES-2 ovarian cancer cells overexpressing the stem cell assoc...

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Detalles Bibliográficos
Autores principales: Price, Zoe K., Lokman, Noor A., Sugiyama, Mai, Koya, Yoshihiro, Yoshihara, Masato, Oehler, Martin K., Kajiyama, Hiroaki, Ricciardelli, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564841/
https://www.ncbi.nlm.nih.gov/pubmed/37815603
http://dx.doi.org/10.1007/s00018-023-04972-9