The autophagy protein Def8 is altered in Alzheimer's disease and Aβ42-expressing Drosophila brains

Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by protein accumulation in the brain as a main neuropathological hallmark. Among them, Aβ42 peptides tend to aggregate and create oligomers and plaques. Macroautophagy, a form of autophagy characterized by a d...

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Detalles Bibliográficos
Autores principales: Oyarce-Pezoa, Sebastián, Rucatti, Guilherme Gischkow, Muñoz-Carvajal, Francisco, Sanhueza, Nicole, Gomez, Wileidy, Espinoza, Sandra, Leiva, Mario, García, Nicolás, Ponce, Daniela P., SanMartín, Carol D., Rojas-Rivera, Diego, Salvadores, Natalia, Behrens, Maria I., Woehlbier, Ute, Calegaro-Nassif, Melissa, Sanhueza, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564863/
https://www.ncbi.nlm.nih.gov/pubmed/37816871
http://dx.doi.org/10.1038/s41598-023-44203-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564863/
https://www.ncbi.nlm.nih.gov/pubmed/37816871
http://dx.doi.org/10.1038/s41598-023-44203-6

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