The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels

The activation of stress response pathways in synovial fibroblasts (SF) is a hallmark of rheumatoid arthritis (RA). CBP and p300 are two highly homologous histone acetyl transferases and writers of activating histone 3 lysine 27 acetylation (H3K27ac) marks. Furthermore, they serve as co-factors for...

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Detalles Bibliográficos
Autores principales: Krošel, Monika, Gabathuler, Marcel, Moser, Larissa, Maciukiewicz, Malgorzata, Züllig, Thomas, Seifritz, Tanja, Tomšič, Matija, Distler, Oliver, Ospelt, Caroline, Klein, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564874/
https://www.ncbi.nlm.nih.gov/pubmed/37816914
http://dx.doi.org/10.1038/s41598-023-44412-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564874/
https://www.ncbi.nlm.nih.gov/pubmed/37816914
http://dx.doi.org/10.1038/s41598-023-44412-z

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