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CD73 deficiency does not aggravate angiotensin II-induced aortic inflammation in mice

Vascular inflammation plays a key role in the development of aortic diseases. A potential novel target for treatment might be CD73, an ecto-5′-nucleotidase that generates anti-inflammatory adenosine in the extracellular space. Here, we investigated whether a lack of CD73 results in enhanced aortic i...

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Detalles Bibliográficos
Autores principales: Massold, Timo, Ibrahim, Fady, Niemann, Viola, Steckel, Bodo, Becker, Katrin, Schrader, Jürgen, Stegbauer, Johannes, Temme, Sebastian, Grandoch, Maria, Flögel, Ulrich, Bouvain, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564884/
https://www.ncbi.nlm.nih.gov/pubmed/37816827
http://dx.doi.org/10.1038/s41598-023-44361-7