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Computational screen for sex-specific drug effects in a cardiac fibroblast signaling network model
Heart disease is the leading cause of death in both men and women. Cardiac fibrosis is the uncontrolled accumulation of extracellular matrix proteins, which can exacerbate the progression of heart failure, and there are currently no drugs approved specifically to target matrix accumulation in the he...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564891/ https://www.ncbi.nlm.nih.gov/pubmed/37816826 http://dx.doi.org/10.1038/s41598-023-44440-9 |