Cargando…

HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes

The class I proteins of the major histocompatibility complex (MHC-I) display epitopic peptides derived from endogenous proteins on the cell surface for immune surveillance. Accurate modeling of peptides bound to the human MHC, HLA, has been mired by conformational diversity of the central peptide re...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Sagar, Nerli, Santrupti, Kutti Kandy, Sreeja, Mersky, Glenn L., Sgourakis, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564892/
https://www.ncbi.nlm.nih.gov/pubmed/37816745
http://dx.doi.org/10.1038/s41467-023-42163-z