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NAT10-dependent N(4)‐acetylcytidine modification mediates PAN RNA stability, KSHV reactivation, and IFI16-related inflammasome activation
N-acetyltransferase 10 (NAT10) is an N(4)‐acetylcytidine (ac(4)C) writer that catalyzes RNA acetylation at cytidine N(4) position on tRNAs, rRNAs and mRNAs. Recently, NAT10 and the associated ac(4)C have been reported to increase the stability of HIV-1 transcripts. Here, we show that NAT10 catalyzes...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564894/ https://www.ncbi.nlm.nih.gov/pubmed/37816771 http://dx.doi.org/10.1038/s41467-023-42135-3 |