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Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer

Metabolic reprogramming has been recognized as one of the major mechanisms that fuel tumor initiation and progression. Our previous studies demonstrate that activation of Drp1 promotes fatty acid oxidation and downstream Wnt signaling. Here we investigate the role of Drp1 in regulating glycogen meta...

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Detalles Bibliográficos
Autores principales: Hasani, Sumati, Young, Lyndsay E. A., Van Nort, Warren, Banerjee, Moumita, Rivas, Dylan R., Kim, Jinhwan, Xiong, Xiaopeng, Sun, Ramon C., Gentry, Matthew S., Sesaki, Hiromi, Gao, Tianyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564897/
https://www.ncbi.nlm.nih.gov/pubmed/37816729
http://dx.doi.org/10.1038/s41419-023-06202-3