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Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer
Metabolic reprogramming has been recognized as one of the major mechanisms that fuel tumor initiation and progression. Our previous studies demonstrate that activation of Drp1 promotes fatty acid oxidation and downstream Wnt signaling. Here we investigate the role of Drp1 in regulating glycogen meta...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564897/ https://www.ncbi.nlm.nih.gov/pubmed/37816729 http://dx.doi.org/10.1038/s41419-023-06202-3 |