SYVN1-mediated ubiquitylation directs localization of MCT4 in the plasma membrane to promote the progression of lung adenocarcinoma

Tumour cells mainly generate energy from glycolysis, which is commonly coupled with lactate production even under normoxic conditions. As a critical lactate transporter, monocarboxylate transporter 4 (MCT4) is highly expressed in glycolytic tissues, such as muscles and tumours. Overexpression of MCT...

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Detalles Bibliográficos
Autores principales: Zhao, Meng, Huang, Chen, Yang, Lexin, Pan, Boyu, Yang, Shuting, Chang, Jiao, Jin, Yu, Zhao, Gang, Yue, Dongsheng, Qie, Shuo, Ren, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564934/
https://www.ncbi.nlm.nih.gov/pubmed/37816756
http://dx.doi.org/10.1038/s41419-023-06208-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564934/
https://www.ncbi.nlm.nih.gov/pubmed/37816756
http://dx.doi.org/10.1038/s41419-023-06208-x

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