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A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis

Mycobacterium tuberculosis phosphoserine phosphatase MtSerB2 is of interest as a new antituberculosis target due to its essential metabolic role in L-serine biosynthesis and effector functions in infected cells. Previous works indicated that MtSerB2 is regulated through an oligomeric transition indu...

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Detalles Bibliográficos
Autores principales: Pierson, Elise, De Pol, Florian, Fillet, Marianne, Wouters, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564941/
https://www.ncbi.nlm.nih.gov/pubmed/37817000
http://dx.doi.org/10.1038/s42003-023-05402-z