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Structure of native chromatin fibres revealed by Cryo-ET in situ

The structure of chromatin plays pivotal roles in regulating gene transcription, DNA replication and repair, and chromosome segregation. This structure, however, remains elusive. Here, using cryo-FIB and cryo-ET, we delineate the 3D architecture of native chromatin fibres in intact interphase human...

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Detalles Bibliográficos
Autores principales: Hou, Zhen, Nightingale, Frank, Zhu, Yanan, MacGregor-Chatwin, Craig, Zhang, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564948/
https://www.ncbi.nlm.nih.gov/pubmed/37816746
http://dx.doi.org/10.1038/s41467-023-42072-1