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Structure of native chromatin fibres revealed by Cryo-ET in situ
The structure of chromatin plays pivotal roles in regulating gene transcription, DNA replication and repair, and chromosome segregation. This structure, however, remains elusive. Here, using cryo-FIB and cryo-ET, we delineate the 3D architecture of native chromatin fibres in intact interphase human...
Autores principales: | Hou, Zhen, Nightingale, Frank, Zhu, Yanan, MacGregor-Chatwin, Craig, Zhang, Peijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564948/ https://www.ncbi.nlm.nih.gov/pubmed/37816746 http://dx.doi.org/10.1038/s41467-023-42072-1 |
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