Single cell transcriptomics reveals recent CD8T cell receptor signaling in patients with coronary artery disease

Coronary artery disease (CAD) is a major cause of death worldwide. The role of CD8+ T cells in CAD is unknown. Recent studies suggest a breakdown of tolerance in atherosclerosis, resulting in active T cell receptor (TCR) engagement with self-antigens. We hypothesized that TCR engagement would leave...

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Detalles Bibliográficos
Autores principales: Iqneibi, Shahad, Saigusa, Ryosuke, Khan, Amir, Oliaeimotlagh, Mohammad, Armstrong Suthahar, Sujit Silas, Kumar, Sunil, Alimadadi, Ahmad, Durant, Christopher P., Ghosheh, Yanal, McNamara, Coleen A., Hedrick, Catherine C., Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565000/
https://www.ncbi.nlm.nih.gov/pubmed/37828989
http://dx.doi.org/10.3389/fimmu.2023.1239148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565000/
https://www.ncbi.nlm.nih.gov/pubmed/37828989
http://dx.doi.org/10.3389/fimmu.2023.1239148

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