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Dual mechanism of Let-7i in tumor progression

Let-7i regulates tumors primarily by binding to the 3′ untranslated region (3′ UTR) of mRNA, which indirectly regulates post-transcriptional gene expression. Let-7i also has an epigenetic function via modulating DNA methylation to directly regulate gene expression. Let-7i performs a dual role by ind...

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Detalles Bibliográficos
Autores principales: Zhou, Jiapei, Xiang, Hongjie, Cao, Zhiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565035/
https://www.ncbi.nlm.nih.gov/pubmed/37829341
http://dx.doi.org/10.3389/fonc.2023.1253191