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Dual mechanism of Let-7i in tumor progression
Let-7i regulates tumors primarily by binding to the 3′ untranslated region (3′ UTR) of mRNA, which indirectly regulates post-transcriptional gene expression. Let-7i also has an epigenetic function via modulating DNA methylation to directly regulate gene expression. Let-7i performs a dual role by ind...
Autores principales: | Zhou, Jiapei, Xiang, Hongjie, Cao, Zhiqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565035/ https://www.ncbi.nlm.nih.gov/pubmed/37829341 http://dx.doi.org/10.3389/fonc.2023.1253191 |
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