Cargando…

Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes

Diabetic kidney disease (DKD) and diabetic peripheral neuropathy (DPN) are common complications of type 1 (T1D) and type 2 (T2D) diabetes. However, the mechanisms underlying pathogenesis of these complications are unclear. In this study, we optimized a streptozotocin-induced db/+ murine model of T1D...

Descripción completa

Detalles Bibliográficos
Autores principales: Elzinga, Sarah E., Eid, Stephanie A., McGregor, Brett A., Jang, Dae-Gyu, Hinder, Lucy M., Dauch, Jacqueline R., Hayes, John M., Zhang, Hongyu, Guo, Kai, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Koubek, Emily J., Feldman, Eva L., Hur, Junguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565109/
https://www.ncbi.nlm.nih.gov/pubmed/37791586
http://dx.doi.org/10.1242/dmm.050080