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The glutamatergic drive to breathe is reduced in severe but not moderate hypoxia in Damaraland mole-rats

Damaraland mole-rats (Fukomys damarensis) are a hypoxia-tolerant fossorial species that exhibit a robust hypoxic metabolic response (HMR) and blunted hypoxic ventilatory response (HVR). Whereas the HVR of most adult mammals is mediated by increased excitatory glutamatergic signalling, naked mole-rat...

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Detalles Bibliográficos
Autores principales: Devereaux, Maiah E. M., Chiasson, Sarah, Brennan, Kate F., Pamenter, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565110/
https://www.ncbi.nlm.nih.gov/pubmed/37589556
http://dx.doi.org/10.1242/jeb.246185