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PUF-8, a C. elegans ortholog of the RNA-binding proteins PUM1 and PUM2, is required for robustness of the cell death fate

During C. elegans development, 1090 somatic cells are generated, of which 959 survive and 131 die, many through apoptosis. We present evidence that PUF-8, a C. elegans ortholog of the mammalian RNA-binding proteins PUM1 and PUM2, is required for the robustness of this ‘survival and death’ pattern. W...

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Detalles Bibliográficos
Autores principales: Xu, Jimei, Jiang, Yanwen, Sherrard, Ryan, Ikegami, Kyoko, Conradt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565243/
https://www.ncbi.nlm.nih.gov/pubmed/37747106
http://dx.doi.org/10.1242/dev.201167