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Compromised junctional integrity phenocopies age-dependent renal dysfunction in Drosophila Snakeskin mutants

Transporting epithelia provide a protective barrier against pathogenic insults while allowing the controlled exchange of ions, solutes and water with the external environment. In invertebrates, these functions depend on formation and maintenance of ‘tight’ septate junctions (SJs). However, the mecha...

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Detalles Bibliográficos
Autores principales: Dornan, Anthony J., Halberg, Kenneth V., Beuter, Liesa-Kristin, Davies, Shireen-Anne, Dow, Julian A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565245/
https://www.ncbi.nlm.nih.gov/pubmed/37694602
http://dx.doi.org/10.1242/jcs.261118