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High-dimensional analysis of T-cell profiling variations following belimumab treatment in systemic lupus erythematosus

OBJECTIVE: This study sought to elucidate the molecular impacts of belimumab (BEL) treatment on T-cell immune profiling in SLE. METHODS: We used mass cytometry with 25 marker panels for T-cell immune profiling in peripheral blood T cells (CD3+) from 22 patients with BEL-treated SLE and 20 controls w...

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Detalles Bibliográficos
Autores principales: Maeda, Shinji, Hashimoto, Hiroya, Maeda, Tomoyo, Tamechika, Shin-ya, Isogai, Shuntaro, Naniwa, Taio, Niimi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565340/
https://www.ncbi.nlm.nih.gov/pubmed/37802602
http://dx.doi.org/10.1136/lupus-2023-000976