Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia

Periventricular neuronal heterotopia (PH) is one of the most common forms of cortical malformation in the human cortex. We show that human neuronal progenitor cells (hNPCs) derived from PH patients with a DCHS1 or FAT4 mutation as well as isogenic lines had altered migratory dynamics when grafted in...

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Detalles Bibliográficos
Autores principales: Bressan, Cedric, Snapyan, Marta, Snapyan, Marina, Klaus, Johannes, di Matteo, Francesco, Robertson, Stephen P, Treutlein, Barbara, Parent, Martin, Cappello, Silvia, Saghatelyan, Armen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565636/
https://www.ncbi.nlm.nih.gov/pubmed/37609821
http://dx.doi.org/10.15252/emmm.202216908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565636/
https://www.ncbi.nlm.nih.gov/pubmed/37609821
http://dx.doi.org/10.15252/emmm.202216908

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