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mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism

Infections with rabies virus (RABV) and related lyssaviruses are uniformly fatal once virus accesses the central nervous system (CNS) and causes disease signs. Current immunotherapies are thus focused on the early, pre‐symptomatic stage of disease, with the goal of peripheral neutralization of virus...

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Detalles Bibliográficos
Autores principales: Mastraccio, Kate E, Huaman, Celeste, Coggins, Si'Ana A, Clouse, Caitlyn, Rader, Madeline, Yan, Lianying, Mandal, Pratyusha, Hussain, Imran, Ahmed, Anwar E, Ho, Trung, Feasley, Austin, Vu, Bang K, Smith, Ina L, Markotter, Wanda, Weir, Dawn L, Laing, Eric D, Broder, Christopher C, Schaefer, Brian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565638/
https://www.ncbi.nlm.nih.gov/pubmed/37767784
http://dx.doi.org/10.15252/emmm.202216394