Cargando…

ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome

Chronic inflammatory diseases are associated with hematopoietic lineage bias, including neutrophilia and anemia. We have recently identified that the canonical inflammasome mediates the cleavage of the master erythroid transcription factor GATA1 in hematopoietic stem and progenitor cells (HSPCs). We...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez‐Ruiz, Lola, Lozano‐Gil, Juan M, Naranjo‐Sánchez, Elena, Martínez‐Balsalobre, Elena, Martínez‐López, Alicia, Lachaud, Christophe, Blanquer, Miguel, Phung, Toan K, García‐Moreno, Diana, Cayuela, María L, Tyrkalska, Sylwia D, Pérez‐Oliva, Ana B, Mulero, Victoriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565642/
https://www.ncbi.nlm.nih.gov/pubmed/37675820
http://dx.doi.org/10.15252/emmm.202318142