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Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli

Xanthohumol, the principle prenylflavonoid found in hops (Humulus lupulus) and a reported anti-inflammatory agent, has great potential for pharmaceutical interventions related to inflammatory disorders in the gut. A suite of probes was prepared from xanthohumol and its structural isomer isoxanthohum...

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Detalles Bibliográficos
Autores principales: Webber, Lucas C., Anderson, Lindsey N., Paraiso, Ines L., Metz, Thomas O., Bradley, Ryan, Stevens, Jan F., Wright, Aaron T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565736/
https://www.ncbi.nlm.nih.gov/pubmed/37829707
http://dx.doi.org/10.1039/d3ra05296f