Biological Activity In Vitro, Absorption, BBB Penetration, and Tolerability of Nanoformulation of BT44:RET Agonist with Disease-Modifying Potential for the Treatment of Neurodegeneration

[Image: see text] BT44 is a novel, second-generation glial cell line-derived neurotropic factor mimetic with improved biological activity and is a lead compound for the treatment of neurodegenerative disorders. Like many other small molecules, it suffers from intrinsic poor aqueous solubility, posin...

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Detalles Bibliográficos
Autores principales: Haider, Malik Salman, Mahato, Arun Kumar, Kotliarova, Anastasiia, Forster, Stefan, Böttcher, Bettina, Stahlhut, Philipp, Sidorova, Yulia, Luxenhofer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565809/
https://www.ncbi.nlm.nih.gov/pubmed/36219820
http://dx.doi.org/10.1021/acs.biomac.2c00761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565809/
https://www.ncbi.nlm.nih.gov/pubmed/36219820
http://dx.doi.org/10.1021/acs.biomac.2c00761

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