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Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation

[Image: see text] Polymeric micelles (PMs) are promising platforms for enhanced tissue targeting of entrapped therapeutic agents. Strategies to circumvent premature release of entrapped drugs include cross-linking of the micellar core as well as covalent attachment of the drug cargo. The chemistry e...

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Detalles Bibliográficos
Autores principales: Hebels, Erik R., Bindt, Felix, Walther, Johanna, van Geijn, Michiel, Weterings, Jimmy, Hu, Qizhi, Colombo, Claudio, Liskamp, Rob, Rijcken, Cristianne, Hennink, Wim E., Vermonden, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565831/
https://www.ncbi.nlm.nih.gov/pubmed/36044412
http://dx.doi.org/10.1021/acs.biomac.2c00865