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Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Cullin-RING finger ligases represent the largest family of ubiquitin ligases. They are responsible for the ubiquitination of ∼20% of cellular proteins degraded through the proteasome, by catalyzing the transfer of E2-loaded ubiquitin to a substrate. Seven cullins are described in vertebrates. Among...

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Detalles Bibliográficos
Autores principales: Raisch, Jennifer, Dubois, Marie-Line, Groleau, Marika, Lévesque, Dominique, Burger, Thomas, Jurkovic, Carla-Marie, Brailly, Romain, Marbach, Gwendoline, McKenna, Alyson, Barrette, Catherine, Jacques, Pierre-Étienne, Boisvert, François-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565876/
https://www.ncbi.nlm.nih.gov/pubmed/37689310
http://dx.doi.org/10.1016/j.mcpro.2023.100644